Clopidogrel-Induced Recurrent Polyarthritis

Clopidogrel-Induced Recurrent Polyarthritis

Clopidogrel is an oral thienopyridine and together with aspirin is a component of dual antiplatelet therapy for the prevention of stent thrombosis after intracoronary stent placement. The common adverse effects from its use are an increased risk of bleeding, neutropenia, and rash. Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with t...

Nivolumab-induced polyarthritis.

Kodama S, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-223387 Description A 48-year-old Japanese woman with non-small cell lung adenocarcinoma (cT3N2M1b) received nivolumab (an immune checkpoint inhibitor) at a dosage of 3 mg/kg every 2 weeks. Treatment with nivolumab was effective. The primary tumour as well as metastases to the lymph nodes and spine almost completely disappeared, as shown o...

Clopidogrel-induced hepatotoxicity.

Clopidogrel-induced liver failure

The thienopyridine derivative clopidogrel (CPG) inhibits ADP-induced platelet activation. It is rapidly hydrolysed in the liver via cytochrome P450 enzymes, by an irreversible and NADPHdependent mechanism. Clopidogrel therapy is indicated in the prevention of thrombotic events in patients with acute coronary syndromes, ischemic stroke and peripheral arterial disease or after percutaneous stent ...

Clopidogrel induced arthritis and fever

Cheng-Fu CAO, Feng ZHANG, Hong Chen, Jun-Xian SONG, Chuan-Fen LIU, Su-Fang LI, Chong-You LEE Department of Cardiology, Peking University People’s Hospital, Beijing, China Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Peking University People’s Hospital, Beijing, China Center for Cardiovascular Translational Research, Peking University People’s Hospi...